Utility of endoscopic pressure study integrated system for gastroesophageal reflux disease after endoscopic antireflux therapy.

Objectives: The endoscopic pressure study integrated system (EPSIS) measures intragastric pressure (IGP) during esophagogastroduodenoscopy. Previous research demonstrated that EPSIS correlates with the 24-h impedance-pH (MII-pH) test and shows lower maximum IGP (IGP-Max) and a flatter waveform gradient in gastroesophageal reflux disease (GERD) patients, attributed to lower esophageal sphincter dysfunction. Although endoscopic antireflux therapy (EARTh) is effective for GERD, the MII-pH monitoring, the gold standard for assessing treatment outcomes, requires hospitalization and can be a burden.

[Endoscopic Treatment for Esophageal Achalasia:Per-oral Endoscopic Myotomy( POEM)].

Per-oral endoscopic myotomy( POEM) is an endoscopic treatment of achalasia. Since the world's first case was performed in Japan in 2008, over 15 years have passed. More than 3,200 cases have been performed at Showa University alone, and over 6,000 cases have been performed throughout Japan.

Phase concept: Novel dynamic endoscopic assessment of intramural antireflux mechanisms (with video).

Objectives: The gastroesophageal junction (GEJ) consists of various anatomical components that together form a barrier to prevent reflux of gastric content. This study introduces a novel phase concept to dynamically evaluate the antireflux barrier (ARB) during endoscopy and analyzes its functionality.

Methods: We reviewed previously the recorded endoscopic videos of subjects who underwent the endoscopic pressure study integrated system (EPSIS) from February to April 2024 for indications other than gastroesophageal reflux disease symptoms.