Publications by authors named "M Ollier"
Introduction: The Canadian Frostbite Collaborative project is exploring frostbite patient care needs and current practices in Canada to inform the development of a Canadian frostbite care network (CFCN) as a national quality improvement initiative.
Methods: Using a quantitative and qualitative approach, this study aimed to define the landscape of current frostbite practices, challenges, and interest in future work.
Results: Current frostbite care practices were initially assessed through semistructured phone interviews of Canadian healthcare providers.
Article Synopsis
- Exonucleasic domain POLE (edPOLE) mutations are found in 1-2% of colorectal cancer (CRC) cases and are linked to a hypermutated tumor phenotype, acting as a potential biomarker for immune checkpoint therapy response.
- This study compared the prevalence of edPOLE mutations in two groups: a control group of unselected CRC patients and a group with unique BRAF/RAS mutations, uncovering that edPOLE mutations were significantly more common in the experimental group (5% vs. 0.45%).
- Among the edPOLE-mutated tumors identified, younger male patients with left-sided tumors showed varying tumor mutational burden (TMB), and the presence of high CD8 tumor
Article Synopsis
- The QTL Fhb1 from spring wheat was successfully introduced into triticale, resulting in enhanced resistance to Fusarium head blight (FHB) across three mapping populations.
- The study involved crossing a highly FHB-resistant experimental line derived from a triticale-wheat cross with modern triticale cultivars, creating recombinant inbred lines for evaluation.
- Four significant QTLs linked to FHB resistance were identified, with one on chromosome 3B matching the Fhb1 locus, marking a major advancement in breeding triticale for improved disease resistance.