Publications by authors named "M Okumi"
Introduction: Radical cystectomy for patients who previously underwent both radical prostatectomy and prostatic bed radiation is technically challenging.
Case Presentation: A 78-year-old man with a history of radical prostatectomy and salvage radiation for prostate cancer was referred to our hospital for radical treatment of bladder cancer. After two cycles of neoadjuvant chemotherapy, he underwent robot-assisted radical cystectomy with real-time transrectal ultrasound guidance during dissection of the rectovesical space to minimize the risk of rectal injury.
Advances in immunosuppressive therapy and postoperative management have greatly improved the graft and patient survival rates after kidney transplantation; however, the incidence of post-transplant malignant tumors is increasing. Post-renal transplantation malignant tumors are associated with renal failure, immunosuppression, and viral infections. Moreover, the risk of developing cancer is higher in kidney transplant recipients than in the general population, and the tendency to develop cancer is affected by the background and environment of each patient.
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- A 48-year-old man with blood in his urine (hematuria) was diagnosed with advanced mucinous bladder adenocarcinoma after imaging and a follow-up evaluation revealed prostate and seminal vesicle invasion and enlarged lymph nodes.
- He underwent robotic-assisted surgery for total bladder removal along with pelvic lymph node dissection, followed by a three-month course of chemotherapy using oxaliplatin and capecitabine (XELOX) due to his high risk of cancer recurrence.
- The patient is currently 8 months post-surgery and shows no signs of cancer progression, highlighting the rarity of mucinous adenocarcinoma of the bladder and the lack of established treatment protocols.
We aimed to retrospectively review outcomes in patients with high-risk prostate cancer and a Gleason score ≤ 6 following modern radiotherapy. We analyzed the outcomes of 1374 patients who had undergone modern radiotherapy, comprising a high-risk low grade [HRLG] group (Gleason score ≤ 6; n = 94) and a high-risk high grade [HRHG] group (Gleason score ≥ 7, n = 1125). We included 955 patients who received brachytherapy with or without external beam radio-therapy (EBRT) and 264 who received modern EBRT (intensity-modulated radiotherapy [IMRT] or stereotactic body radiotherapy [SBRT]).
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