Publications by authors named "M Okudaira"

Article Synopsis
  • - This study investigated how motor unit (MU) firing patterns differ between older hypertensive (both treated and untreated) and normotensive individuals during exercise, particularly focusing on knee extension activities and measuring their blood pressure response afterward.
  • - Results showed that treated hypertensive individuals had lower MU firing rates compared to both untreated hypertensive and normotensive groups, and the change in systolic blood pressure (SBP) after exercise was more significant in treated hypertensives.
  • - The research found a positive correlation between MU firing rates and SBP change only in untreated hypertensive individuals, indicating that their MU firing patterns were linked to blood pressure responses post-exercise, a relationship not seen in the other groups.
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Article Synopsis
  • * The research involved a multicenter point-prevalence survey of 10,199 patients across 27 hospitals in Aichi Prefecture, revealing a 6.6% rate of HAIs, with pneumonia, urinary tract infections, and surgical site infections being the most common.
  • * The study concludes that the findings are crucial for understanding HAIs in Japan and stresses the importance of national-level surveys to monitor healthcare challenges, especially in the context of post-COVID-19 conditions.
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Hedgehog (Hh) signaling pathway dysregulation is involved in the pathogenesis of metabolic dysfunction-associated steatohepatitis, and the sonic Hh (SHh) protein, a pivotal molecule in the Hh pathway, is expressed in ballooned hepatocytes. The present study aimed to investigate the clinicopathological significance of SHh expression in steatohepatitic hepatocellular carcinoma (SH-HCC). Reverse transcription-quantitative polymerase chain reaction and immunohistochemistry were performed to examine gene and SHh protein expression in SH-HCC.

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Objective: To describe the development and maturation of equine proximal sesamoid bones (PSBs) in fetuses and young horses using radiography, microcomputed (micro)-CT, and histology.

Methods: A descriptive study. Forelimb PSBs from 12 equids ranging in age from 105 days of gestation to 540 days postgestation were evaluated.

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We investigated the effects of one-week quercetin ingestion on motor unit (MU) behavior and muscle contractile properties before, during, and after a single session of resistance exercise in older adults. Twenty-four older adults were divided into two groups: those receiving quercetin glycosides (QUE) or placebo (PLA), and they performed a single session of resistance exercise. MU behavior before and during resistance exercise and electrically elicited contraction before and after resistance exercise were measured (Day 1), and the same measurements were conducted again after 7 days of placebo or quercetin glycoside ingestion (Day 8).

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