Publications by authors named "M Ohta"
Background: This phase 3 open-label study evaluated the efficacy and safety of ceftazidime-avibactam in Japanese patients with complicated intra-abdominal infections (cIAIs).
Methods: Hospitalised adults with cIAI received ceftazidime-avibactam + metronidazole for 5-14 days. The primary efficacy endpoint was clinical cure at the test-of-cure (TOC) visit in the clinically evaluable (CE) analysis set.
Background: Fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) for chronic coronary syndromes (CCS) improves outcomes compared with angiography-guided PCI, however cardiac events still occur during long-term follow-up of FFR-negative patients. In the PREVENT study preventive PCI reduced cardiac-events in lesions which were FFR-negative (FFR > 0.80) and had intracoronary imaging defined vulnerable plaque.
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- The study evaluated a 3-month oral hypofunction management protocol that included oral function training and dietary advice for older patients with oral hypofunction.
- Results showed significant improvements in the nutritional status of the intervention group, evidenced by an increased Mini Nutritional Assessment score, while the control group showed no changes.
- The findings suggest that combining nutritional guidance with functional training can effectively enhance both oral function and nutritional status in older adults suffering from oral hypofunction.
Article Synopsis
- The study examines how bariatric/metabolic surgery affects the incidence and severity of COVID-19 among patients in Japan, amidst ongoing debates about its protective benefits.
- Data were collected from 83 institutions, revealing that while there were no severe cases or deaths among 119 patients studied, moderate COVID-19 cases were notably more prevalent in these bariatric patients than in the general population.
- The findings suggest that bariatric/metabolic surgery does not reduce the risk of COVID-19 complications, as moderate cases were linked to specific risk factors such as dyslipidemia and prior infection.
Aim: Pregnant women are at increased risk for severe illness associated with coronavirus disease 2019 (COVID-19) compared to nonpregnant women. The aim of this multicenter prospective study was to assess the current COVID-19 vaccination status of pregnant women in the southern Osaka district and to compare their antibody titers with those of nonpregnant women.
Methods: Serum antibody titers of anti-NCP antibodies (antibodies against the SARS-CoV-2 nucleocapsid) and anti-RBD antibodies (the receptor binding domain of the S1 subunit of the spike protein) were evaluated in 753 pregnant women at 34-35 weeks of gestation from October 2021 to March 2022.