[Evaluation of fibrotic effects from dusts originating from KWK "Brzeszcze" on lung tissue].

In order to determine biological aggressiveness of settled dusts and dusts collected using the gravimetric method, experimental studies were carried out, including: 1) evaluation of the physicochemical parameters (size of dust particles, content of silica, metals and other chemical compounds); 2) evaluation of the haemolytic activity; 3) experimental of evaluation fibrogenic potentials by means of: a) intraperitoneal test--to identify morphological type of reactive changes in peritoneum and; b) intratracheal test--to determine the level of hydroxyproline (collagen) in lungs and the morphological type of reactive changes. Albino rats were used for the experiment. The animals were divided into ten groups which received a single intratracheal injection of 50 mg of mining dust in 0.

[Comparative analysis of biological aggressiveness of dusts from different coal mines for determining the risk of development of pneumoconiosis among miners].

The aim of the study was to determine the changes in the respiratory system of animals administered intratracheally settled dusts sampled from the following coal mines: "Debieńsko" in Leszczyny, "Zabrze" in Zabrze, "Gliwice" in Gliwice, "Janina" in Libiaz and "Victoria" in Wałbrzych. Total dustiness in those mines in 1985-1988 was found to be as follows: "Debieńsko"--1.39 mg/m3-22.

[Biological attestation of the fibrogenic effect of dust from selected coal mines on the lung tissue].

The studies aimed at determining the changes in respiratory system of animals after intratracheal administration of settled dusts sampled from seams 116 and 188 in Janina colliery and seams 314 and 317 in Victoria colliery. For comparison, dusts sampled gravimetrically from a/m seams in Janina and Victoria collieries were intratracheally administered to animals. Crystalline silica concentrations determined by Polezajew method in dusts from Janina and Victoria collieries were 2.

[Evaluation of the fibrogenic effect of coke dust on the lungs and internal organs of experimental animals].

Based on the data collected by the Provincial Regional Administration Unit for Control of Epidemics and Hygiene in Katowice, dust concentration at the MAKOSZOWY Coking Plant in Zabrze at 18 work-places exceeded the TLV's. The purpose of this study was to determine changes within the respiratory systems of experimental animals exposed to intratracheal administration of MAKOSZOWY Coking Plant dust, sampled at the charging larry 3-4 operating stand and at the battery roof. After pulverization the dusts contained 98.