Publications by authors named "M Oberniedermayr"
In an analysis of 84 primary-operated breast cancer patients and 11 healthy donors, we found that the bone marrow of most patients contained memory T cells with specificity for tumor-associated antigens. Patients' bone marrow and peripheral blood contained CD8+ T cells that specifically bound HLA/peptide tetramers. In short-term culture with autologous dendritic cells pre-pulsed with tumor lysates, patients' memory T cells from bone marrow (but not peripheral blood) could be specifically reactivated to interferon-gamma-producing and cytotoxic effector cells.
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- Advances in treatment for proximal femur fractures have simplified decision-making for medical professionals, based on a review of technical developments and patient data.
- Extracapsular fractures are categorized into pertrochanteric and unstable intratrochanteric fractures, with specific fixation methods like dynamic hip screws and condylar plates used for treatment.
- Intracapsular fracture treatment varies by age: younger patients typically receive screw osteosynthesis to preserve the femoral head, while older patients may need head resection and total prosthesis, with a simplified approach for those with limited life expectancy.