Publications by authors named "M Obayashi"
Bovine lactoferrin (bLF) is a 77 kDa glycoprotein that is abundant in bovine breast milk and exerts various bioactive functions, including antibacterial and antiviral functions. Few studies have explored bLF activity against parasites. We found that bLF affects hemozoin synthesis by binding to heme, inhibiting heme iron polymerization necessary for Plasmodium berghei ANKA survival in infected erythrocytes, and also binds to hemozoin, causing it to disassemble.
View Article and Find Full Text PDFBackground/aim: A few case reports of central nervous system (CNS) symptoms caused by amantadine intoxication have been published, detailing various types of symptoms and differing times to onset. We encountered a patient who developed CNS symptoms with amantadine. This prompted us to investigate the types, time to onset, and outcome of CNS adverse reactions to amantadine by analyzing data from a pharmacovigilance database.
View Article and Find Full Text PDFBackground: We report a case of anaphylaxis induced by natto (fermented soybeans) allergy that occurred following dermal sensitization from a jellyfish sting.
Case Presentation: A 49-year-old male presented to the emergency room complaining of an acute onset of erythema with pruritis that appeared while he was surfing. Given that his heart rate dropped to ~ 40 bpm without a decline in blood pressure or oxygen saturation, we suspected anaphylaxis and administered 0.
Article Synopsis
- The study investigated whether a collaborative nursing care delivery system (4 nurses for 2 patients) could reduce patient safety events (PSEs) compared to a traditional system (1 nurse for 2 patients).
- Conducted in Japan, the study compared outcomes for 561 patients in the traditional system with 401 patients in the collaborative system, including critical analyses of patient demographics.
- Results indicated no significant difference in PSEs between the two groups, but the collaborative system showed a statistically significant decrease in occurrences of PSEs, suggesting its potential benefits in intensive care settings.
Article Synopsis
- * A retrospective analysis of 248 VLBWIs suggested that factors such as gestational age, birth weight, and enteral nutrition impact citrulline levels over time, indicating that these levels change as infants mature.
- * Citrulline levels appear to reflect a shift from catabolism (breaking down) to synthesis (building up) that occurs as fetal growth progresses and after birth, positioning citrulline as a potential indicator for assessing intestinal health.