Publications by authors named "M OEztuerk"
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) of still unclear etiology. In recent years, the search for biomarkers facilitating its diagnosis, prognosis, therapy response, and other parameters has gained increasing attention. In this regard, in a previous meta-analysis comprising 22 studies, we found that MS is associated with higher nitrite/nitrate (NOx) levels in the cerebrospinal fluid (CSF) compared to patients with non-inflammatory other neurological diseases (NIOND).
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- Inflammatory neuromuscular disorders are immune-mediated diseases with varied symptoms and treatment responses, making it crucial to identify specific biomarkers for better understanding and management.
- This review focuses on biomarkers in conditions like Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, myasthenia gravis, and idiopathic inflammatory myopathy, highlighting their diagnostic and prognostic roles and the need for more specific biomarkers.
- Although current biomarkers have potential to enhance disease management, challenges in their reliability and the rarity of these disorders underscore the necessity for further research and novel approaches in biomarker development.
Determination of subvisible particle (SVP) content in biopharmaceuticals is a prerequisite to ensure the quality of liquid biopharmaceutical products. Here, we present a comparison of the recently introduced holographic video microscopy (total holographic characterization, THC) with two orthogonal and well-established analytical technologies: micro flow imaging (MFI) and resonant mass measurement (RMM). The capabilities of the THC were investigated under conditions commonly applied in drug product development.
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