Transient receptor potential vanilloid 1 involved in the analgesic effects of total flavonoids extracted from Longxuejie ().

Objective: To evaluate the analgesic effects of total flavonoids of Longxuejie () (TFDB) and explore the possible analgesic mechanism associated with transient receptor potential vanilloid 1 (TRPV1).

Methods: Whole-cell patch clamp technique was used to observe the effects of TFDB on capsaicin-induced TRPV1 currents. Rat experiments were used to observe the analgesic effects of TFDB.

Laparoscopic management of obturator nerve schwannomas: experiences with 6 cases and review of the literature.

Objectives: To present our experiences in management of obturator nerve schwannomas by laparoscopy.

Patients And Methods: Six patients who were diagnosed preoperatively with pelvic tumors and histologically with obturator nerve schwannomas were treated by laparoscopy in our hospital between 1998 and 2009. Clinical data were obtained by a retrospective review of all the patients' medical records, radiologic reports, pathologic reports, and operation videos.