Machine Learning Algorithms Associate Case Numbers with SARS-CoV-2 Variants Rather Than with Impactful Mutations.

During the SARS-CoV-2 pandemic, much effort has been geared towards creating models to predict case numbers. These models typically rely on epidemiological data, and as such overlook viral genomic information, which could be assumed to improve predictions, as different variants show varying levels of virulence. To test this hypothesis, we implemented simple models to predict future case numbers based on the genomic sequences of the Alpha and Delta variants, which were co-circulating in Texas and Minnesota early during the pandemic.

Participation restrictions at work indicate participation restrictions in other domains of life.

Health problems are often associated with activity limitations and participation restrictions, as defined in the International Classification of Functioning, Disability and Health (ICF). This often affects the workplace in the form of sick leave or a reduction in productivity. The question is, "to what extent are participation restrictions at work related to participation restrictions in other domains of life?" A total of 382 primary health care patients (aged 18-65) were asked to provide information on their employment status, perceived health-related workplace problems and sick leave status.

[Intraoperative molecular assessment of sentinel nodes in the breast cancer using the Gene Search BLN Assay technique: our experience about 126 patients].

Introduction: Intraoperative molecular assay Gene Search BLN Assay (BLN) detects sentinel lymph node (SLN) metastasis in breast cancer. Our objective was to compare BLN to the definitive conventional histologic methods and to experiment the management of BLN in routine.

Material And Methods: Each SLN was cut into alternate slabs.

[Minimal emotional dysfunction and first impression formation in personality disorders].

"Minimal cerebral dysfunctions" are isolated impairments of basic mental functions, which are elements of complex functions like speech. The best described are cognitive dysfunctions such as reading and writing problems, dyscalculia, attention deficits, but also motor dysfunctions such as problems with articulation, hyperactivity or impulsivity. Personality disorders can be characterized by isolated emotional dysfunctions in relation to emotional adequacy, intensity and responsivity.