Publications by authors named "M O Tebruegge"
Article Synopsis
- Immune-based TB diagnostic tests currently have low sensitivity in children and struggle to differentiate between latent TB infection (LTBI) and active TB disease.
- The study analyzed 17 biomarkers in plasma from children with confirmed TB, LTBI, and non-TB infections, finding significant biomarkers like IFN-γ and IL-2 that effectively predicted TB status.
- The IFN-γ/MCP-1 ratio emerged as the most promising combination for distinguishing between MTB-infected and non-infected children, suggesting a need for further research to improve pediatric TB diagnosis.
(1) Background: Data on persisting symptoms after SARS-CoV-2 infection in children and adolescents are conflicting. Due to the absence of a clear pathophysiological correlate and a definitive diagnostic test, the diagnosis of Long COVID currently rests on consensus definitions only. This review aims to summarise the evidence regarding Long COVID in children and adolescents, incorporating the latest studies on this topic.
View Article and Find Full Text PDFBackground: Tuberculosis (TB) poses a major public health challenge, particularly in children. A substantial proportion of children with TB disease remain undetected and unconfirmed. Therefore, there is an urgent need for a highly sensitive point-of-care test.
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