Global Epidemiology and Implications of I148M Variant in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Systematic Review and Meta-analysis.

Background & Aims: rs738409 variant is a risk factor for onset and progression of metabolic dysfunction-associated steatotic liver disease (MASLD). We aimed to assess its global prevalence, clinical and histological characteristics, and long-term outcomes in patients with MASLD.

Methods: PubMed and Embase databases were searched until December 30, 2023, for observational studies on genotyped adults with MASLD.

Mandibular ossifying fibroma in 2 cattle in Brazil.

Ossifying fibroma (OF) is a slow-growing, expansive, and benign fibro-osseous neoplasm that is rare in cattle. It mainly affects the craniofacial bones, especially the mandible. Here, we report 2 cases of mandibular OF in Nelore and mixed-breed steers with enlarged masses in the rostral portion of the mandible.

The Brazilian Portuguese Version of the Behavioral Regulation in Exercise Questionnaire 3 (BREQ-3) Is Reliable and Valid for Assessing Motivational Regulations and Self-Determination in Exercise Among Adults Aged 50 Years or Older: A Methodological Study.

The study aimed to investigate the reliability, construct, and discriminant validity of the Behavioral Regulation in Exercise Questionnaire 3 (BREQ-3) for evaluating motivational regulations and self-determination for exercise in Brazilian adults aged 50 years or older. The study assessed motivation for exercise, peripheral muscle strength, physical performance, functional capacity, cardiovascular fitness, and frailty phenotype. Two raters independently applied the BREQ-3.