Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors.

Background: Brain metastases and primary high-grade gliomas, including glioblastomas multiforme (GBM) and anaplastic astrocytomas (AA), may be indistinguishable by conventional magnetic resonance (MR) imaging. Identification of these tumors may have therapeutic consequences.

Purpose: To assess the value of MR spectroscopy (MRS) using short and intermediate echo time (TE) in differentiating solitary brain metastases and high-grade gliomas on the basis of differences in metabolite ratios in the intratumoral and peritumoral region.

Microphthalmia and brain atrophy: a novel neurodegenerative disease.

Objective: To delineate the features of a novel neurodegenerative disease.

Methods: We report three children of three related families with congenital microphthalmia and blindness, and progressive spasticity, microcephaly, seizures, and profound mental retardation.

Results: A magnetic resonance imaging scan was normal at birth.

Acute osteomyelitis as a complication of varicella.

Varicella is a common viral infection in childhood, and acute osteomyelitis is one of the rare but serious complications. We report two cases of osteomyelitis as a complication of varicella. The possibilities and limitations of the different imaging modalities are discussed, as well as imaging findings during the course of this condition.

[Skeletal tuberculosis--diagnostic challenges].

Background: Skeletal tuberculosis is rare in Norway. The diagnosis could be difficult.

Material: A Somalian mother and three daughters and a Somalian girl in the neighborhood developed skeletal tuberculosis 4-12 months after arrival in Norway.