Publications by authors named "M O Asani"
Article Synopsis
- The study focuses on optic neuritis (ON) as a potential early sign of multiple sclerosis (MS) and develops a predictive model to identify patients at risk of developing MS.
- Data from the Optic Neuritis Treatment Trial included 457 patients, with a final analysis of 388 patients revealing that specific factors like MRI lesions and ON type significantly influence the risk of developing clinically definite MS.
- The decision tree model demonstrated a decent accuracy of around 70%, helping physicians make informed decisions about patient care based on individual risk factors.
Background: Obstructive sleep apnea (OSA), characterized by recurrent partial or complete upper airway obstructions during sleep, is an established risk factor for cardiovascular diseases in children. This study aims to determine the prevalence of left ventricular hypertrophy (LVH), abnormal left ventricular (LV) geometric patterns, and diastolic dysfunction in children with OSA and compare them with healthy controls.
Materials And Methods: This was a cross-sectional comparative study conducted on 75 eligible children with OSA aged 2-14 years and 75 age- and sex-matched healthy children.
Article Synopsis
- This study evaluates the effects of brimonidine on visual functions, specifically contrast sensitivity in patients with acute optic neuritis.
- Conducted as a randomized clinical trial with 60 participants, it compared the outcomes of those treated with brimonidine to a control group receiving synthetic tears over three months.
- Results showed significant improvements in contrast sensitivity and visual acuity for the brimonidine group, indicating its potential neuroprotective benefits for retinal ganglion cell function.
Introduction: Predicting the conversion of clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (CDMS) is critical to personalizing treatment planning and benefits for patients. The aim of this study is to develop an explainable machine learning (ML) model for predicting this conversion based on demographic, clinical, and imaging data.
Method: The ML model, Extreme Gradient Boosting (XGBoost), was employed on the public dataset of 273 Mexican mestizo CIS patients with 10-year follow-up.
Background: Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is accepted as the gold standard treatment for center-involving diabetic macular edema (CI-DME). Adjunctive administration of topical dorzolamide may enhance the therapeutic effects of anti-VEGF agents. In this study, we compared the efficacy of topical dorzolamide plus intravitreal injection of bevacizumab (IVB) versus IVB alone in patients with bilateral DME.
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