Can serum orexin levels be used as a marker in childhood epilepsy?

Objective: Epilepsy is one of the most common neurological diseases in the pediatric population. Orexins are excitatory peptides and associated with energy homeostasis, eating and drinking behaviors, sleep regulation, sleep-wake periods, analgesia, and cognitive activities such as attention, learning, and memory. The aim of this study was to reveal the relationship between plasma orexin levels and seizures in pediatric epilepsy patients with seizures, epilepsy patients in remission, and healthy control group with similar demographic characteristics.

Speed breeding advancements in safflower ( L.): a simplified and efficient approach for accelerating breeding programs.

This study investigated the potential of extended irradiation combined with immature embryo culture techniques to accelerate generation advancements in safflower ( L.) breeding programs. We developed an efficient speed breeding method by applying light-emitting diodes (LEDs) that emit specific wavelengths, alongside the in vitro germination of immature embryos under controlled environmental conditions.

A New Approach for Infrared Temperature Measurement Sensor Systems and Temperature Control for Domestic Induction Hobs.

The accurate measurement of cooking vessel temperatures in induction hobs is crucial for ensuring optimal cooking performance and safety. To achieve this, improvements in existing measurement methods such as thermocouples, thermistors, and infrared (IR) temperature sensors are being explored. However, traditional IR sensors are sensitive to interference from the heated glass ceramic, severely affecting accuracy.

Shear Wave Elastography in AV Fistula Thrombosis: Differentiating Thrombus Age and Assessing Clinical Outcomes of Balloon Angioplasty.

Objectives: To evaluate the role of shear wave elastography (SWE) in distinguishing acute from subacute thrombi in thrombosed arteriovenous fistulas (AVFs) and explore the relationship between thrombus stiffness and outcomes of balloon angioplasty.

Materials And Methods: This retrospective study included 44 dialysis patients with thrombosed AVFs from June 2022 to June 2024. Patients underwent Doppler ultrasound and SWE to assess thrombus age, followed by balloon angioplasty.

Unsymmetric triazine-based triglucoside detergents for membrane protein stability.

Membrane proteins play a crucial role in a variety of biological processes and are key targets for pharmaceutical development. Structural studies of membrane proteins provide molecular insights into the mechanisms of these processes and are essential for effective drug discovery. Historically, these studies have relied on solubilization of the target protein using detergents, but conventional detergents often fail to maintain the stability of challenging membrane proteins.