Segregation distortion has been reported to occur in a number of the trinucleotide repeat disorders. On the basis of a sperm typing study performed in patients of Japanese descent with Machado-Joseph disease (MJD), it was reported that disease alleles are preferentially transmitted during meiosis. We performed a sperm typing study of five MJD patients of French descent and analysis of the pooled data shows a ratio of mutant to normal alleles of 379:436 (46.
View Article and Find Full Text PDFThe surface complexation model is used to describe sorption experiments of inorganic mercury(II) in the presence of an amorphous silica, Aerosil 200, or an iron (hydr)oxide, the goethite alpha-FeOOH (Bayferrox 910). In the simulations, one assumes the formation of a monodentate surface complex &tbond;S&bond;OHg(+) and of ternary surface complexes with OH(-) surface groups, &tbond;S&bond;OHgOH and &tbond;S&bond;OHgCl, when chlorides are present in solution. Participation of the complex &tbond;S&bond;OHgCl has been especially evidenced.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 1998
In order to characterize the structure of the surface complexes formed by interaction between uranyl and europium (III) ions and the surface of solid matrices, optical and X-ray photoelectron spectroscopies experiments on uranyl/europium loaded phosphate solids (Th4P2O7(PO4)4, ZrP2O7, and Zr2O(PO4)2) have been performed. The use of complimentary spectroscopic techniques allows an identification of the sorption mechanism and a structural characterization of the sorption sites and the sorbed species on phosphate surfaces. The samples were prepared from aqueous uranyl or europium solutions in the pH range from 1.
View Article and Find Full Text PDFHuman embryo cryopreservation represents an indispensable extension of in-vitro fertilization (IVF) programmes as long as they are based upon the recovery of a large number of oocytes. The most widely used procedures include the cryopreservation of human zygotes or embryos in early cleavage, using 1,2-propanediol and sucrose as cryoprotectants. Our results over a 10 year period (1986-1995) on 5032 thawed cycles involving 14 222 stored embryos make it possible to appraise the results and the contribution of embryo freezing to assisted reproduction.
View Article and Find Full Text PDFOocytes donation is managed by two bioethic french laws. We will have a look at the enforcement of these in comparaison with their non specificity.
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