Publications by authors named "M Nyunga"
Background: Cancer patients who are exposed to sepsis and had previous chemotherapy may have increased severity. Among chemotherapeutic agents, anthracyclines have been associated with cardiac toxicity. Like other chemotherapeutic agents, they may cause endothelial toxicity.
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- A study examined the prevalence of PTSD among ICU survivors after being treated for COVID-19 compared to other causes of ICU admission, finding that 4.9% of patients in both groups had a presumptive diagnosis of PTSD six months later.
- After adjusting for factors like age and prior trauma, COVID-19 status alone was not linked to PTSD diagnosis, although female patients were more likely to exhibit PTSD symptoms.
- Patients treated for COVID-19 did report higher levels of specific PTSD symptoms like intrusion and avoidance when compared to those treated for other conditions, indicating different psychological impacts.
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- The study investigates the impact of socio-economic status on respiratory issues in survivors of ARDS due to COVID-19, finding that 40% of patients were socio-economically deprived.
- After a follow-up of 6 months post-ICU, 80% of the 401 patients showed respiratory issues, but socio-economic status did not significantly affect the prevalence of these complications.
- The results suggest that, regardless of socio-economic background, the majority of ARDS survivors experienced respiratory sequelae, indicating the widespread impact of COVID-19 on lung health.
Background: Immune checkpoint inhibitors (ICI) have revolutionized the management of cancer. They can induce immune-related adverse events (irAE) leading to intensive care unit (ICU) admission. We aimed to describe irAEs for ICU admissions in solid cancer patients treated with ICIs.
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