Publications by authors named "M Notarnicola"
Article Synopsis
- Very low-calorie ketogenic diets (VLCKD) effectively aid weight loss in obese individuals and can decrease liver condition risks.
- Small extracellular vesicles (sEVs) from serum are studied in obese adults to see how they affect liver fibrosis and inflammation, with participants divided into low and high fibrosis risk groups.
- Results show that sEVs from low-risk patients improved liver health markers, while those from high-risk patients worsened inflammation and fibrosis signals, stressing the importance of assessing sEVs alongside traditional methods like FibroScan.
The condition of cellular senescence has specific features, including an altered lipid metabolism. Delta-9 desaturase (Δ9) catalyzes the conversion of saturated fatty acids, such as palmitic acid and stearic acid, into their monounsaturated forms, palmitoleic and oleic acid, respectively. Δ9 activity is important for most lipid functions, such as membrane fluidity, lipoprotein metabolism and energy storage.
View Article and Find Full Text PDFIn quantum communication protocols, the use of photon-number-resolving detectors could open new perspectives by broadening the way to encode and decode information and merging the properties of discrete and continuous variables. In this work, we consider a quantum channel exploiting a silicon-photomultiplier-based receiver and evaluate its performance for quantum communication protocols under three possible configurations, defined by different post-processing of the detection outcomes. We investigate two scenarios: information transmission over the channel, quantified by the mutual information, and continuous-variable quantum key distribution, quantified by the key generation rate.
View Article and Find Full Text PDFBackground/objectives: Metabolic dysfunction-associated fatty liver disease (MAFLD) is currently the most common cause of chronic liver disease. Systemic inflammatory status and peripheral metabolic symptoms in the clinical picture have an impact on gut commensal bacteria.
Methods: Our designed clinical trial was based on a cohort of patients with MAFLD whose diet included the daily consumption of 400 g of "Navelina" oranges for 28 days, compared with a control group of patients with the same pathologic conditions whose diet did not include the consumption of oranges and other foods containing similar nutrients/micronutrients.
Article Synopsis
- Early-stage gastric cancer often goes undetected due to a lack of specific symptoms, resulting in late diagnoses and advanced disease, highlighting the need for new biomarkers for early detection and treatment matching.
- The study investigated the prognostic significance of ENPP2/Autotaxin (ATX) and lysophosphatidic acid (LPA) in Gastro-Esophageal Adenocarcinoma (GEA), finding that higher levels of these substances could indicate worse patient outcomes.
- Results showed that while ENPP2 mutations are infrequent, they are linked to lower overall survival, and surgical removal of tumors significantly reduced serum ATX and LPA levels, suggesting potential for targeted therapies based on these biomarkers in future clinical trials.