Publications by authors named "M Nojima"
Background: The involvement of Mediterranean fever (MEFV) gene mutations in patients with inflammatory bowel disease unclassified (IBDU) remains unclear. This study aimed to determine the clinical characteristics and responsiveness to colchicine in Japanese patients with IBDU carrying MEFV mutations.
Methods: In this retrospective cohort study, we examined MEFV mutations using gene analysis, clinical information, and colchicine responsiveness.
Article Synopsis
- The study investigates non-acquired immunodeficiency syndrome-defining malignancies (NADMs) among people living with hemophilia and HIV in Japan, focusing on the period after the approval of direct-acting antivirals for hepatitis C virus (HCV).
- A nationwide survey was conducted across 395 HIV treatment facilities, collecting data on 328 individuals from 2015 to 2022, which revealed that liver cancer was the most common NADM, accounting for 43% of cases identified.
- The findings indicate a significantly higher rate of liver cancer and other malignancies in this population, particularly in younger patients, emphasizing the importance of regular cancer screening and preventive strategies for PLWH
Objectives: With physician maldistribution recognised as a global issue, Japan implemented the physician uneven distribution (PUD) index as a strategic measure. Currently, there is a lack of objective assessment of core clinical competencies in regions influenced by varying levels of physician distribution. In this study, we objectively assess the core clinical competencies in regions affected by physician maldistribution and explore the relationship between the PUD index and the clinical competencies of resident physicians.
View Article and Find Full Text PDFThe majority of dermatitis cases in adults result from chronic or relapsing atopic dermatitis in childhood. Adult-onset atopic dermatitis, also known as idiopathic chronic eczematous eruption of aging (CEEA), is a phenomenon seen in adults 50 years and older with no prior history of atopic dermatitis. CEEA is often a diagnosis of exclusion after ruling out more serious causes of dermatitis including bullous pemphigoid (BP), allergic conditions, and hematologic malignancies.
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