The paradoxical activity of BRAF inhibitors: potential use in wound healing.

The area of wound healing presents a promising field of interest for clinicians as well as the scientific community. A major concern for physicians is the rising number of elderly people suffering from diabetes, leprosy, tuberculosis and the associated chronic wounds. While traditional therapies target basic wound care, innovative strategies that accelerate wound healing are needed.

Aldosterone and Potassium in Heart Failure: Overcoming This Major Impediment in Clinical Practice.

Aldosterone is a key regulator of fluid and electrolyte balance in the body. It is often dysregulated in heart failure (HF) and is a key driver of cardiac remodelling and worse clinical outcomes. Potassium regulation is essential for normal cardiac, gastrointestinal and neuromuscular function.

Exploring the Research Landscape of Transcranial Direct Current Stimulation in Stroke: A Bibliometric Review.

Transcranial direct current stimulation (tDCS) has gained significant attention as a potential therapeutic tool in stroke rehabilitation, promoting neuroplasticity and enhancing motor and cognitive recovery. Despite growing research, the field's evolution and key trends remain underexplored. This study aims to perform a bibliographic analysis of publications related to tDCS and stroke rehabilitation to assess the growth of the field.

β-Caryophyllene and Statins in Bone Fracture Healing - A Narrative Review.

Bone fractures are a leading cause of morbidity and healthcare expenditure globally. The complex healing process involves inflammation, cartilage formation, mineralization, and bone remodeling. Current treatments like immobilization, surgery, and bone grafting, though effective, pose significant challenges, such as prolonged recovery and high costs.

Efficacy and safety of anti-CD38 monoclonal antibodies-based therapy versus standard therapy in newly diagnosed multiple myeloma patients: a systematic review and meta-analysis.

Background: Anti-CD38 monoclonal antibodies (mAbs) have significantly changed the multiple myeloma treatment landscape. This meta-analysis compared the efficacy and safety of anti-CD38 mAb-based therapy versus standard therapy in newly diagnosed multiple myeloma (NDMM) patients.

Methods: We performed a comprehensive literature search on PubMed, the Cochrane Database, and ClinicalTrials.