Publications by authors named "M Nikaido"
Background: Although health insurance claims data can address questions that clinical trials cannot answer, the uncertainty of disease names and the absence of stage information hinder their use in gastric cancer (GC) research. This study aimed to develop and validate a claims-based algorithm to identify and determine the progression phases of incident GC cases in Japan.
Methods: The gold standard for validation in this retrospective observational study was medical records of patients with incident GC who underwent specific treatments, defined by the claim codes associated with GC treatment.
Article Synopsis
- - The ancient vomeronasal receptor type-1 (ancV1R) is important for pheromone sensing and is found in many vertebrates, but its specific function is not yet fully understood.
- - Researchers studied female mice lacking ancV1R and found that these mice showed rejection of male sexual behavior and did not respond to male urine as potential mating cues.
- - The absence of ancV1R disrupted the normal physiological responses in the vomeronasal organ, leading to abnormal sexual behaviors and increased stress responses when in contact with males, suggesting its key role in mate recognition.
The olfactory organ of tetrapods, with few exceptions, comprises the main and accessory organs: olfactory epithelium (OE) and vomeronasal organ (VNO). Unlike tetrapods, teleost fish lack a VNO. However, lungfish, a type of sarcopterygian fish closely related to tetrapods, possesses a lamellar OE similar to the OE of teleosts and a recess epithelium (RecE) resembling the amphibian VNO.
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