Children's perspectives on being absorbed when reading fiction: A Q methodology study.

Research in the intersections of literature, media, and psychology increasingly examines the absorbing story experiences of adult readers, typically relying on quantitative self-report questionnaires. Meanwhile, little work has been done to explore how being "lost in a book" is experienced by children, despite the phenomenon's importance for literacy education. Such work requires tools that are more inductive and child-centered than questionnaires.

Comparison of three corneal trephines for use in therapeutic penetrating keratoplasties for large corneal perforations.

Corneas with large perforations complicate penetrating keratoplasty due to the increased risk of anterior chamber collapse they pose. We hypothesize that suction trephines should produce more uniform corneal openings than non-suction trephines. Penetrating keratoplasties using Franceschetti-type freeblades, and Hanna and Hessberg-Barron suction trephines were performed on human eye bank eyes with large corneal perforations.

Effect of the CH2NH and CH2NAc peptide bond isosteres on the antagonistic and histamine releasing activities of a luteinizing hormone-releasing hormone analogue.

The effect of the CH2NH and CH2NAc peptide bond isosteres on the antagonistic and histamine releasing activities of the LH-RH antagonist [N-Ac-D-Nal1,D-Phe2,3,D-Arg6,Phe7,D-Ala10] LH-RH was investigated. The moieties were introduced by facile, racemization-free solid-phase synthesis in an attempt to reduce the histamine releasing activity inherent to the most potent analogues while retaining high antiovulatory activity. The psi [CH2NH] isostere was incorporated at each CONH site with the exception of 8-9, which involves Pro, by reductive alkylation with a protected amino acid aldehyde in the presence of NaBH3CN during conventional solid-phase peptide synthesis.

Accumulation of ornithine by chick retinal pigment epithelium cells in culture.

This study was designed to measure the accumulation of ornithine in retinal pigment epithelium cells grown in culture. Ornithine accumulated in retinal pigment epithelium cells in which the ornithine aminotransferase activity was inhibited with L-canaline. The effect of L-canaline was eliminated by the concomitant presence of methionine.

Effect of reductive alkylation of lysine in positions 6 and/or 8 on the histamine-releasing activity of luteinizing hormone-releasing hormone antagonists.

The solid-phase reductive alkylation of the Lys side chain in positions 6 (D) and 8 (L) and position 8 alone of the LH-RH antagonist [N-Ac-D-Nal,D-Ph2,3,D-Arg6,Phe7,D-Ala10]LH-RH was investigated in an attempt to reduce the histamine-releasing activity inherent to most potent antagonists while retaining high antiovulatory activity. The protected parent analogues were prepared by conventional solid-phase peptide synthesis. After selective removal of the Lys Fmoc side chain protection, the resin-bound peptides were readily and conveniently alkylated at the epsilon amino groups with various aldehydes and ketones in the presence of NaBH3CN.