Immunoadjuvant therapy in the regulation of cell death in sepsis: recent advances and future directions.

Sepsis is characterized by a concomitant early pro-inflammatory response by immune cells to an infection, and an opposing anti-inflammatory response that results in protracted immunosuppression. The primary pathological event in sepsis is widespread programmed cell death, or cellular self-sacrifice, of innate and adaptive immune cells, leading to profound immunological suppression. This severe immune dysfunction hampers effective primary pathogen clearance, thereby increasing the risk of secondary opportunistic infections, latent viral reactivation, multiple organ dysfunction, and elevated mortality.

Analysis of jute-glass fiber reinforced epoxy hybrid composite.

This study investigated a composite material combining epoxy with hybrid jute (J) and glass (G) fibers. A straightforward and effective fabrication method was employed, utilizing five layers with various reinforcement materials. To identify the optimal combination, a comprehensive series of tests were conducted using a range of characterization instruments, including Scanning Electron Microscopy (SEM), Universal Testing Machine (UTM), pendulum impact tester, density measurement, specific gravity evaluation, water absorption, and swelling thickness tests.

Effect of essential oils as vitamin C preservatives and chia seed ) in the fortification of pineapple jam.

The present investigation "Effect of essential oils and chia seed () in fortification of pineapple jam." was conducted during the year 2022-2023 at the Post harvest laboratory of Horticulture Department, Sher-e-Bangla Agricultural University, Dhaka. The study investigated the effects of essential oil and chia seeds on the quality of pineapple jam.

Medically assisted integrated rehabilitation program for people with opioid dependence: a quasi-experimental evaluation using multi-criteria decision analysis.

Background: Opioid use disorders constitute a vast disease burden, need for comprehensive treatment, and substantial costs to individuals, families, and society. The multifaceted needs of people with opioid dependence call for integrated care. The study aims to assess the added value of an integrated medically assisted rehabilitation (MAR) program providing opioid agonist therapy for patients with opioid dependence as compared to the standard of care (SoC) in Norway.

Electrochemical Selective Nitrate Reduction: Pathways to Nitrogen and Ammonia Production.

Nitrate (NO ) contamination from industrial, agricultural, and anthropogenic activities poses significant risks to human health and ecosystems. While traditional NO remediation methods are effective, they often generate secondary pollutants and incur high costs. Electrochemical NO reduction (ECNR) offers a sustainable alternative, converting NO into environmentally benign nitrogen (N) or valuable ammonia (NH).