Publications by authors named "M Natalia Stelmaszuk"

Background: With advent of newer treatments for psoriasis, real-world use of biologics in Japan is evolving.

Methods: This retrospective study utilized data from patients with ≥1 psoriasis-related biologic claims record between January 2016 and December 2020 in Japan to evaluate treatment patterns, healthcare resource utilization (HCRU), and associated costs. Data were analyzed using descriptive statistics.

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This non-interventional, observational, longitudinal study describes treatment patterns of atopic dermatitis (AD) in Sweden. Data from 3 Swedish registries were merged, and included patients who received an AD diagnosis (during the period 1997 to 2019) and had AD treatment prescribed (during the period 2006 to 2020). Treatment persistence, treatment sequencing, time-to-event analysis, and 12-month prevalence were analysed.

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Article Synopsis
  • Evidence on how dosages of biologic treatments for psoriasis are adjusted in real-world scenarios is limited but may carry significant clinical and economic consequences.
  • A study conducted in Sweden from 2010 to 2018 reviewed the dosage adjustments of four biologics used for treating moderate to severe psoriasis, finding that average dosages often exceeded recommended levels.
  • The results suggest that frequent dose increases may reflect a belief in inadequate effectiveness of these treatments, impacting their associated costs and overall cost-effectiveness, highlighting the need for more research on this issue.
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The diagnosis of duodenal adenocarcinoma is still a complex gastrological and oncological problem. The described case illustrates the unusual character of the course, the reasonableness of the diagnostic procedures and the scope of the therapy undertaken. The causes of anemia, which was the first symptom of the disease, were not revealed in the tests carried out at this stage - gastroscopy, colonoscopy, with normal other basic laboratory tests.

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Small intestine tumors are rarely diagnosed as they constitute only 0.6% of all malignant tumors, including about 1-3% of malignant neoplasms of the gastrointestinal tract. They also advocate for 0.

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