Publications by authors named "M Nagler"
Background: Early detection and diagnosis of venous thromboembolism are vital for effective treatment. To what extent methodological shortcomings exist in studies of diagnostic tests and whether this affects published test performance is unknown.
Objectives: We aimed to assess the methodological quality of studies evaluating diagnostic tests for venous thromboembolic diseases and quantify the direction and impact of design characteristics on diagnostic performance.
In spite of my personal belief in the benefits of artificial intelligence (AI), reading Cathy O'Neil's book "Weapons of Math Destruction" left me feeling unsettled.1 She describes how flawed and unchecked algorithms are widely applied in areas that affect us all: hiring, credit scoring, access to education, and insurance pricing. In one example, a fixed percentage of teachers in a U.
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- The study evaluates the diagnostic significance of two immunoassay tests for heparin-induced thrombocytopenia (HIT) using data from 1393 patients, aiming to clarify the reliability of test results across their ranges.
- Findings reveal that while both assays correlate results to HIT diagnoses, the strength of this correlation differs, with the CLIA method showing a more pronounced increase in likelihood ratios compared to the ELISA method.
- A web-based calculator is provided to help clinicians estimate the probability of HIT based on individual test results, enhancing decision-making in patient care.
The use of machine-learning (ML) algorithms in medicine has sparked a heated discussion. It is considered one of the most disruptive general-purpose technologies in decades. It has already permeated many areas of our daily lives and produced applications that we can no longer do without, such as navigation apps or translation software.
View Article and Find Full Text PDFMyocardial injury after noncardiac surgery (MINS) and perioperative myocardial injury are associated with increased morbidity and mortality. Both are diagnosed by a perioperative increase in troponin, yet there is controversy if MINS is a genuine myocardial insult. We applied postoperative cardiovascular magnetic resonance T2 mapping techniques to visualise acute myocardial injury (i.
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