Multidrug-Resistant Bacteria in Surgical Intensive Care Units: Antibiotic Susceptibility and β-Lactamase Characterization.

Multidrug-resistant (MDR) bacteria of the utmost importance are extended-spectrum β-lactamase (ESBL) and carbapenemase-producing Enterobacterales (CRE), carbapenem-resistant (CRAB), carbapenem-resistant (CRPA), methicillin-resistant (MRSA) and vancomycin-resistant spp. (VRE). In this study, an evaluation of MDR bacteria in surgical intensive care units in a tertiary referral hospital was conducted.

Solithromycin in Children and Adolescents With Community-acquired Bacterial Pneumonia.

Background: Solithromycin is a new macrolide-ketolide antibiotic with potential effectiveness in pediatric community-acquired bacterial pneumonia (CABP). Our objective was to evaluate its safety and effectiveness in children with CABP.

Methods: This phase 2/3, randomized, open-label, active-control, multicenter study randomly assigned solithromycin (capsules, suspension or intravenous) or an appropriate comparator antibiotic in a 3:1 ratio (planned n = 400) to children 2 months to 17 years of age with CABP.

Giant appendix or an appendiceal mucocele? Case report of an 11-year-old child.

We present an 11-year-old male child with an enormous appendix that was regarded as an appendiceal mucocele. The disorder is very rare and usually appears in middle aged patients. It is a clinical diagnosis.

Skeletal evidence of trepanning on a 5th century skull from Ludbreg, Croatia.

This paper presents a case of skull trepanation from the town of Ludbreg in north-western Croatia. This is the second case of trepanation reported in human skeletal remains from archaeological sites in Croatia. The procedure was performed on an adult male buried in a tomb under tegulae at the "Somođi Garden" site.