Synergistic effects of and on human colorectal adenocarcinoma cell proliferation.

Background And Objectives: Colorectal cancer (CRC) is a common type of cancer that has a high death rate and is becoming more common in developed countries. Currently, there are several treatment options available for CRC patients, and clinical trials are being conducted to improve conventional therapies. This study investigates the combined impact of (B.

Updates on current evidence for biologics in chronic rhinosinusitis.

Purpose Of Review: The purpose of this review is to present the most important recent developments concerning biologics as a therapeutic option for chronic rhinosinusitis (CRS).

Recent Findings: mAb anti-IL-4 receptor α (Dupilumab) was recently approved by Food and Drug Administration (FDA) for patients with CRSwNP and four other biologics are under investigation, with promising preliminary results.

Summary: CRS is a disease associated with a significant symptom burden and high-indirect costs.

Serum cholesterol concentration and distress in the initial days after childbirth.

The link between mood disorders and cholesterol is characterized by some contradictory data. In particular, it is not clear whether health factors are responsible for lowered cholesterol levels and mood swings. The present study tests the association between serum cholesterol level and psychological distress in women in two different post-delivery hospital settings: rooming-in (RI) and no rooming-in (no-RI).

Profile of Mood States and parental attitudes in motherhood: comparing women with planned and unplanned pregnancies.

Background: Despite the availability of various contraceptive options, in some Western countries most pregnancies are unplanned. The objective of this longitudinal study was to assess the influence of planned and unplanned pregnancy on women's psychological well-being and on maternal attitude toward parenting in the first years after giving birth.

Methods: A sample of 119 primiparous women (88 planned and 31 unplanned pregnancies) with normal pregnancy, uncomplicated vaginal delivery, and a healthy living baby completed the Profile of Mood States (POMS) instrument in the ninth month of pregnancy, and at 1, 6, and 12 months after birth, and the Parental Attitude Research Instrument (PARI) 2 years after the birth.