Publications by authors named "M NAGAYAMA"

Purpose: To identify a method for comparing preoperative axial length (AL) measurements with postoperative AL in submacular hemorrhage (SMH).

Study Design: Retrospective.

Methods: This study included 30 patients who underwent vitrectomy for SMH (January 2016-January 2023) with preoperative and postoperative AL data.

View Article and Find Full Text PDF

Background: Hepatic encephalopathy (HE) is a severe complication of acute hepatic failure requiring urgent critical care management. Branched-chain amino acids (BCAAs) such as leucine, isoleucine, and valine have been investigated as potential treatments to improve outcomes in patients with acute HE. However, the effectiveness of BCAA administration during the acute phase remains unclear.

View Article and Find Full Text PDF

Activation of brown and beige fat biogenesis promotes metabolic health in rodents and humans, but typically requires cold exposure or pharmacological activation of β-adrenergic receptors, which may pose cardiovascular risks. Dietary intervention represents a clinically viable alternative strategy to induce beige cells and thus enhance metabolic health, though the underlying mechanisms remain poorly understood. In this study, we identified specific microbiota members in both mice and humans that promote browning of white adipose tissue (WAT) and ameliorate metabolic disorders in the context of a low-protein diet (LPD).

View Article and Find Full Text PDF
Article Synopsis
  • * The study involved 202 GC patients diagnosed after H. pylori eradication, separating them into those diagnosed within 10 years (S10AE) and those diagnosed after (L10AE), with findings showing longer surveillance intervals for L10AE cases and a higher prevalence of submucosal invasion.
  • * A multivariate analysis suggested that being diagnosed with GC at L10AE significantly correlates with deeper tissue invasion (submucosal or deeper), indicating that follow-ups shouldn't be unnecessarily
View Article and Find Full Text PDF

Surface modification with functional molecules is essential for introducing various surface properties. As gold nanoparticles (AuNPs) have extraordinary chemical, physical, and optical properties, control of their surface, mainly through modification with mixed alkanethiols Au-S interactions, has attracted much attention. However, surface modification of AuNPs with mixed alkanethiols to provide a strictly regulated composition remains challenging.

View Article and Find Full Text PDF