Publications by authors named "M N Sinanan"

Article Synopsis
  • - Early-onset colorectal cancer is increasing in Western populations, particularly in patients under 50, who make up 21% of a study sample of 2,193 colorectal cancer patients.
  • - Early-onset patients generally presented with more advanced disease (stages III-IV) compared to older patients and received more aggressive treatments regardless of their disease stage.
  • - Factors influencing early-onset cases include a higher likelihood of being never smokers and a lower likelihood of being overweight, indicating different lifestyle or demographic patterns between early and late-onset patients.
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Objective: The use of text messaging in clinical care has become ubiquitous. Due to security and privacy concerns, many hospital systems are evaluating secure text messaging applications. This paper highlights our evaluation process, and offers an overview of secure messaging functionalities, as well as a framework for how to evaluate such applications.

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Objective: To describe long-term quality of life (QOL) outcomes after rectourethral fistula (RUF) repair. RUF is a debilitating diagnosis and complex surgical dilemma with limited data regarding QOL after repair.

Methods: Patients at a tertiary referral center undergoing transperineal RUF repair 1/2009-5/2016 were analyzed.

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Background: Plasma microRNAs (miRNAs) are promising non-invasive biomarkers for colorectal cancer (CRC) prognosis. However, the published studies to date have yielded conflicting and inconsistent results for specific plasma miRNAs.

Methods: We have conducted a study using robust assays to assess a panel of nine miRNAs for CRC prognosis and early detection of recurrence.

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