Publications by authors named "M N Mowafy"

Article Synopsis
  • - The Hepatitis B virus (HBV) vaccine uses purified surface antigens produced through recombinant DNA technology, targeting a specific region on the virus to induce neutralizing antibodies.
  • - A case study highlighted a vaccinated patient infected with an HBV strain (Eg200) that escaped the vaccine, belonging to genotype D and an uncommon sub-genotype D9 found in Egypt.
  • - The analysis revealed double mutations in a crucial part of the virus (T125M and P127T) that still aligns with the detected serotype of the vaccine escape strain, underscoring the need for ongoing surveillance of such strains for improving vaccination strategies.
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The spread of fluoroquinolone (FQ) resistance in Acinetobacter baumannii represents a critical health threat. This study aims to overcome FQ resistance in A. baumannii via the formulation of polymeric nanoFQs.

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Article Synopsis
  • Hepatitis B virus (HBV) is a major cause of viral hepatitis globally, and it has four key proteins that are crucial for its function, including HBcAg.
  • This study details a method for cloning and expressing HBcAg using PCR and E. coli, leading to successful protein production verified by SDS-PAGE and Western blotting.
  • The synthesized HBcAg was effectively used in diagnosing HBV infections by detecting anti-HBcAg antibodies in patient serum, highlighting its potential for HBV research and diagnosis.
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Hepatocellular carcinoma (HCC) is one of the global health concerns. Hepatitis B virus (HBV) is one of the major causes of HCC. Poor clinical outcome of HCC patients is attributed to a small population of cancer cells known as cancer stem cells (CSCs).

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Background: The cognitive process of critical thinking (CT) involves the examination of the existing reasons and an analysis of the information to draw conclusions and make decisions. The goal of the study was to determine how concept mapping (CM) technique affects family medicine residents' capacity for critical thought.

Materials And Methods: We conducted a randomized controlled trial among family medicine residents aged between 26 and 28 years.

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