The pathogenesis of COVID-19 warrants unravelling. Genetic polymorphism analysis may help answer the variability in disease outcome. To determine the role of KIR and HLA polymorphisms in susceptibility, progression, and severity of SARS-CoV-2 infection, 458 patients and 667 controls enrolled in this retrospective observational study from April to December 2020.
View Article and Find Full Text PDFDaptomycin is one of the last therapeutic resources for multidrug-resistant gram-positive bacteria. Despite its structural similarities with glycopeptides, its mechanisms of action and resistance are different and in some respects are not completely understood. Mutations in several genes have been associated with daptomycin resistance, especially in , , and , but their role and importance remain to be elucidated.
View Article and Find Full Text PDFEnferm Infecc Microbiol Clin (Engl Ed)
October 2023
Introduction: Human dermatophytoses are the most widespread infections caused by fungi. These are capable of invading the keratin-containing tissues of animals. Nannizzia nana (N.
View Article and Find Full Text PDFObjective: The increase in morbidity and mortality associated the influenza virus infections represents an important global challenge, with particular relevance within health institutions.The aim of the study was to highlight the impact, repercussions and characteristics of the nosocomial transmission of influenza virus.
Methods: A sample of 286 hospitalized patients in a third-level hospital with confirmed influenza (virus RNA in respiratory specimens) is included.