A bimodal association of vitamin D levels and vascular disease in children on dialysis.

In addition to its classical role in calcium-phosphate homeostasis, vitamin D has anti-inflammatory effects that may influence vascular disease. This study examined the impact of vitamin D levels on the vascular phenotype in 61 children who had been on dialysis for >or=3 mo and in 40 age-matched control subjects. All dialysis patients were prescribed daily oral 1-alpha hydroxyvitamin D(3).

Being a pretty good citizen: an analysis and monetary valuation of formal and informal voluntary work by gender and educational attainment.

This paper is set in the context of macrosocial/macroeconomic theories of the organization of both paid and unpaid work. The specific topic investigated is engagement in unpaid voluntary work, an activity which is thought to be important for social cohesion, civil society and citizenship. Research on the sources of social cohesion has focused on organizational membership and voluntary organization activity.

Walking behaviours from the 1965-2003 American Heritage Time Use Study (AHTUS).

Background: The American Heritage Time Use Study (AHTUS) represents a harmonised historical data file of time use by adults, amalgamating surveys collected in 1965-66, 1975-76, 1985, 1992-94, and 2003. The objectives of time-use studies have ranged from evaluating household and other unpaid production of goods and services, to monitoring of media use, to comparing lifestyles of more and less privileged social groups, or to tracking broad shifts in social behaviour. The purpose of this paper is to describe the process and utility of identifying and compiling data from the AHTUS to describe a range of walking behaviours collected using time-use survey methods over almost 40 years in the USA.

GENDER CONVERGENCE IN THE AMERICAN HERITAGE TIME USE STUDY (AHTUS).

We present evidence from a new comprehensive database of harmonized national time-diary data that standardizes information on almost 40 years of daily life in America. The advantages of the diary method over other ways of calculating how time is spent are reviewed, along with its ability to generate more reliable and accurate measures of productive activity than respondent estimates or other alternatives. We then discuss the various procedures used to develop these harmonized data, both to standardize reporting detail and to match with Census Bureau population characteristics.

Blood 5-hydroxytryptamine, 5-hydroxyindoleacetic acid and melatonin levels in patients with either Huntington's disease or chronic brain injury.

Following a study of oxidative tryptophan metabolism to kynurenines, we have now analysed the blood of patients with either Huntington's disease or traumatic brain injury for levels of 5-hydroxytryptamine (5-HT), 5-hydroxyindoleacetic acid (5-HIAA) and melatonin. There were no differences in the baseline levels of these compounds between patients and healthy controls. Tryptophan depletion did not reduce 5-HT levels in either the controls or in the patients with Huntington's disease, but it increased 5-HT levels in patients with brain injury and lowered 5-HIAA in the control and Huntington's disease groups.