Publications by authors named "M N Darboe"

Article Synopsis
  • - The study investigated the prevalence of post-tuberculosis lung disease (PTLD) among children and adolescents in The Gambia, focusing on survivors of pulmonary tuberculosis (pTB).
  • - Out of 79 participants, a significant number experienced respiratory issues after treatment, including cough and abnormal lung function as indicated by chest X-rays (CXR) and spirometry tests.
  • - Factors like age at diagnosis, undernutrition, and lung fibrosis were linked to poorer lung function, highlighting the need for ongoing monitoring and evaluation post-TB treatment to enhance patient outcomes.
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Background: Early initiation of breastfeeding within the first hour of life prevents neonatal and infant mortality. Sustainable Development Goals (SDGs) Target 3.2 aims to reduce neonatal mortality and under 5 mortality globally.

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Background: Body image concerns are prevalent and are viewed as risk factors for engaging in unhealthy weight control behaviors (UWCBs), such as purging, fasting, and the misuse of laxatives and diet pills. Studies have also linked UWCBs to the development of eating disorders. In the United States (U.

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Beta amyloid cleaving enzyme 1 (BACE1) is largely expressed by neurons and is the sole β-secretase for initiating the production of neuronal β-amyloid peptides (Aβ). To fully understand the physiological functions of neuronal BACE1, we used mouse genetic approach coupled with unbiased single nucleus RNA sequencing (snRNAseq) to investigate how targeted deletion of Bace1 in neurons, driven by Thy-1-Cre recombinase, would affect functions in the nervous system. Our transcriptome results revealed that BACE1 is essential for maturation of neural precursor cells and oligodendrocytes in mice.

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In 2013, the Government of The Gambia implemented a novel results-based financing (RBF) intervention designed to improve maternal and child nutrition and health through a combination of community, facility and individual incentives. In a mixed-methods study, we used a randomized 2 × 2 study design to measure these interventions' impact on the uptake of priority maternal health services, hygiene and sanitation. Conditional cash transfers to individuals were bundled with facility results-based payments.

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