Publications by authors named "M N Courel"

RNA binding proteins (RBPs) and their associated partners are key factors of posttranscriptional control of gene expression. To study and manipulate the functional consequences of binding of these regulators to their targets, several tethering assays have been developed, in which a protein of interest is brought to a reporter mRNA through heterologous RNA-protein interaction motifs. The effect of such constrained binding is then monitored by measuring the accumulation of the reporter protein and mRNA.

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Article Synopsis
  • Understanding RNA targeting to membraneless organelles like P-bodies (PBs) is crucial for revealing their functions in cells.
  • This study shows that PBs in HEK293 cells undergo significant changes in RNA content throughout the cell cycle, with different mRNA localization patterns appearing at various stages (G1, S, G2).
  • The findings suggest that PBs actively sort mRNAs based on their translation status and characteristics, implying that they play a more dynamic role than merely housing excess untranslated mRNAs.
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In this work, we present a theoretical study on the use of CuZnSn(S,Se) quantum wells in CuZnSnS solar cells to enhance device efficiency. The role of different well thickness, number, and S/(S + Se) composition values is evaluated. The physical mechanisms governing the optoelectronic parameters are analyzed.

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A numerical simulation is a valuable tool since it allows the optimization of both time and the cost of experimental processes for time optimization and the cost of experimental processes. In addition, it will enable the interpretation of developed measurements in complex structures, the design and optimization of solar cells, and the prediction of the optimal parameters that contribute to manufacturing a device with the best performance. In this sense, a detailed simulation study was carried out in this work by the Solar Cell Capacitance Simulator (SCAPS).

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Following the chronological stages of calculations imposed by the WIEN2K code, we have performed a series of density functional theory calculations, from which we were able to study the effect of strain on the kesterite structures for two quaternary semiconductor compounds Cu2ZnGeS4 and Cu2ZnGeSe4. Remarkable changes were found in the electronic and optical properties of these two materials during the application of biaxial strain. Indeed, the band gap energy of both materials decreases from the equilibrium state, and the applied strain is more pronounced.

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