Publications by authors named "M Mutignani"
Intestinal permeability has been related to colorectal cancer (CRC) development. Zonulin, a protein able to regulate tight junction function and intestinal permeability, emerges as a promising marker to elucidate the contribution of bacterial translocation in CRC. An Italian case-control study included 77 CRC cases, 72 intestinal adenoma and 76 healthy controls (for a total of 148 tumor-free subjects), aged 20-85.
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- The text refers to a correction made to a previously published article.
- The specific article mentioned can be identified by its DOI, which is 10.1055/a-2411-1814.
- Corrections like this are common in academic publishing to address errors or inaccuracies in research.
Article Synopsis
- - The study investigated outcomes of lumen-apposing metal stents (LAMS) placement in patients with surgically altered anatomy (SAA), which is not well-documented in existing literature, involving 270 patients across 25 tertiary care centers up to November 2023.
- - Technical success of the procedures was very high at 98%, with clinical success at 97%, although there was a notable adverse event rate of 12%, with various degrees of severity recorded.
- - The results suggest that while LAMS placement in SAA is effective, due to the risk of complications, these procedures should only be performed by experienced endoscopists in specialized centers.
Background And Aim: In surgically altered anatomy (SAA), endoscopic retrograde cholangiopancreatography (ERCP) can be challenging, and it remains debatable the choice of the optimal endoscopic approach within this context. We aim to show our experience and evaluate the technical and clinical success of endoscopic treatment performed in the setting of adverse events (AE) after pancreaticoduodenectomy (PD).
Methods: This study was conducted on a retrospective cohort of patients presenting biliopancreatic complications after PD from 01/01/2012 to 31/12/2022.