Publications by authors named "M Muthuraman"
Article Synopsis
- The study investigates the relationship between optical spectral transmission (OST) and markers of clinical inflammatory arthritis in patients diagnosed with rheumatic diseases.
- OST measurements were taken from 1,312 joints of 60 patients at two different times, comparing results with clinical activity measures like DAS28 and swollen joint counts.
- Findings showed that OST scores were significantly higher in patients with inflammatory arthritis, and changes in OST values were closely related to changes in clinical activity markers, suggesting OST could be a useful tool for monitoring disease activity.
Naringin-templated magnetic molecularly imprinted polymers for selective quercetin extraction from onion peel.
J Chromatogr B Analyt Technol Biomed Life Sci
November 2024
Article Synopsis
- A Magnetic Molecularly Imprinted Polymer (MMIP) was created using naringin as a template molecule and acrylamide as a functional monomer, utilizing ultrasound to enhance its ability to adsorb naringin.
- Surprisingly, the MMIP showed a stronger affinity for quercetin than for its intended target, naringin, leading to further studies on its adsorption properties and kinetics.
- The research led to a maximum adsorption capacity of 7.2 mg/g for quercetin and 4.9 mg/g for naringin, and quercetin was successfully quantified from onion peel waste using the MMIP combined with HPLC-UV technology.
Immune dysregulation in the brain and periphery is thought to contribute to the detrimental neurodegeneration that occurs in Parkinson's disease (PD). Identifying mechanisms to reverse this dysregulation is key to developing disease-altering therapeutics for this currently incurable disease. Here we utilized the longitudinal data from the Parkinson's Progression Marker Initiative to demonstrate that circulating lymphocytes progressively decline in PD and can be used to predict future motor symptom progression.
View Article and Find Full Text PDFAmyotrophic lateral sclerosis (ALS) is characterised primarily by motor system degeneration, with clinical evidence of cognitive and behavioural change in up to 50% of cases. We have shown previously that resting-state EEG captures dysfunction in motor and cognitive networks in ALS. However, the longitudinal development of these dysfunctional patterns, especially in networks linked with cognitive-behavioural functions, remains unclear.
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