[From perceived dangerousness to the dangerous individual: clinical challenges and vision of society].

It is a complex task to identify individuals who are persistently dangerous for others because of a mental disorder. The results of unstructured clinical interviews are poor. Risk assessment instruments statistically improve the prediction of violence.

Trazodone addition for insomnia in venlafaxine-treated, depressed inpatients: a semi-naturalistic study.

In this paper, we present the results of a prospective semi-naturalistic study of the addition of trazodone for insomnia to a 4 week, 300mg/day venlafaxine treatment in 50 depressed inpatients. The Montgomery and Asberg depression rating scale was used as a rating instrument. The study is designated as semi-naturalistic due to the fact that, although the venlafaxine treatment regimen was strictly defined, the timing of the trazodone introduction and the dosage were determined by the clinicians.

Lithium augmentation in venlafaxine non-responders: an open study.

Thirteen major depressive patients not responding to a 4-week venlafaxine 300 mg treatment were eligible for a 4-week open trial of lithium addition. Two patients had to stop lithium for a possible moderate serotonin syndrome and five patients became responders, including one dramatic response and two semi-rapid responses.