Publications by authors named "M Muranaka"
Background: Accumulating evidence suggests that rapid eye movement sleep (REM) supports the consolidation of extinction memory. REM is disrupted in posttraumatic stress disorder (PTSD), and REM abnormalities after traumatic events increase the risk of developing PTSD. Therefore, it was hypothesized that abnormal REM in trauma-exposed individuals may pave the way for PTSD by interfering with the processing of extinction memory.
View Article and Find Full Text PDFEvaluation of stopping power ratio of artificial breast implants for carbon-ion radiotherapy.
Radiol Phys Technol
March 2025
The number of patients requiring breast reconstruction with artificial implants has been increasing, and so is the use of carbon-ion radiotherapy (CIRT). Consequently, a growing number of patients with artificial breast implants are expected to undergo CIRT. Because artificial breasts are composed of a silicone polymer gel with a silicon-oxygen backbone, which differs significantly from human tissues, the stopping power ratio for carbon beams cannot be accurately converted from CT values using standard CT-to-stopping power ratio tables (CT-SP tables).
View Article and Find Full Text PDFArticle Synopsis
- Penile Mondor's disease (PMD) is a rare and usually benign condition caused by thrombophlebitis of the superficial dorsal vein of the penis, but in this case, it was a sign of lung adenocarcinoma.
- A 46-year-old Japanese man initially presented with PMD, which led to the diagnosis of advanced stage IVA lung cancer, complicated by deep vein thrombosis and nonbacterial thrombotic endocarditis.
- This case emphasizes the need for doctors to consider potential underlying cancers in patients with unusual clotting issues, as well as the varied ways cancer can present itself.
Localization of silica nanoparticles to lysosome causes lysosomal dysfunction in JEG-3 cells.
Biochem Biophys Res Commun
December 2024
Nanoparticles have useful functions due to the characteristics conferred on them by an increase in their specific surface area, and they have already been put into practical use in products in various industrial fields. Although exposure to nanoparticles in daily life is unavoidable for pregnant women, studies that evaluate the toxicity of nanoparticles in pregnant women are lacking. To redress this, we have focused on the placenta and have previously revealed that nanoparticles can show placental toxicity.
View Article and Find Full Text PDFBackground: Not only gray matter lesions (GMLs) but also white matter lesions (WMLs) can play important roles in the pathology of Alzheimer's disease (AD). The progression of cognitive impairment (CI) and behavioral and psychological symptoms of dementia (BPSD) might be caused by a concerted effect of both GML and WML.
Objective: This study aimed to investigate the association between GML and WML and how they are involved in the symptoms of CI and BPSD in dementia patients by means of imaging technology.