A genome-wide association study of anti-Müllerian hormone (AMH) levels in Samoan women.

Study Question: Can a genome-wide association study (GWAS) and transcriptome-wide association study (TWAS) help identify genetic variation or genes associated with circulating anti-Müllerian hormone (AMH) levels in Samoan women?

Summary Answer: We identified eleven genome-wide suggestive loci (strongest association signal in 19-946163-G-C [ = 2.32 × 10⁻⁷]) and seven transcriptome-wide significant genes ( [all with a < 2.50 × 10⁻⁶]) associated with circulating AMH levels in Samoan women.

A Study on Factors Causing Prehospital Delay in Treatment of Status Epilepticus.

Objective: To identify factors causing prehospital delay in treatment of status epilepticus (SE).

Materials And Methods: This is a prospective observational study done on 78 patients with SE in the Stanley Medical College, Chennai, over 2 years. Demographic SE-related data and treatment delay were entered and correlated with outcome.

Bacterial Rps3 counters oxidative and UV stress by recognizing and processing AP-sites on mRNA via a novel mechanism.

Lesions and stable secondary structures in mRNA severely impact the translation efficiency, causing ribosome stalling and collisions. Prokaryotic ribosomal proteins Rps3, Rps4 and Rps5, located in the mRNA entry tunnel, form the mRNA helicase center and unwind stable mRNA secondary structures during translation. However, the mechanism underlying the detection of lesions on translating mRNA is unclear.

Ternion Approach of Surgical Coverage in Single Tooth Recession: A Case Report on a Novel Technique.

The goal of mucogingival surgery or periodontal plastic surgery is to preserve gingiva, remove aberrant frenum or muscle attachments, increase vestibular depth, and correct the denuded root surface. Recession coverage is indeed a challenging technique, whereas covering the exposed roots is not only important for aesthetic reasons but also for preventing further issues such as tooth sensitivity, root decay, and loss of supporting bone. A coronally advanced flap (CAF) is one of the most common procedures done for recession coverage because of the concept that the coronal advancement of a flap without tension to cover the exposed root surface or CAF with autogenous grafts results in bulk and improves the thickness of the gingival tissue, increasing the stability and aesthetics of the result.

Frenectomy Managed by a Bilateral Pedicle Flap: A Case Report.

In the oral cavity, the frenum is an anatomical structure composed of mucosal folds that connect the lip and cheek to the alveolar mucosa, gingiva, and underlying periosteum. An abnormally positioned maxillary labial frenum can contribute to the formation of a diastema and gingival recession. Various techniques have been proposed for the correction of aberrant frenal attachments, including frenectomy and frenal repositioning procedures.