Publications by authors named "M Mumjitha"

Article Synopsis
  • - The study developed pectin-based biocomposite films integrated with nucleobases (cytosine, thymine, uracil) to create a drug delivery system for the anticancer drug 5-Fluorouracil (5-FU), utilizing bio-multiple hydrogen bonds for stabilization.
  • - Various characterization methods (FTIR, XRD, TGA, SEM) were used to assess the films' properties, revealing that adding nucleobases slowed down the release of 5-FU, particularly in acidic conditions (pH 1.2).
  • - Testing showed that the PC-NB-5-FU films were safe for blood use and effective in promoting cellular uptake and increasing cancer cell apoptosis,
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Poly(vinyl alcohol) (PVA) is reinforced with TiO2 nanoparticles in order to enhance thermo-mechanical stabilities, surface characteristics and osteoblastic cell adhesion. PVA-TiO2 nanocomposite films with desirable mechanical, thermal and biocompatible properties are fabricated through solution casting method followed by de-hydrothermal cross-linking treatment. The composition of TiO2 nanoparticles was standardized to achieve mechanically stable nanocomposite films, based on tensile strength measurements composition of TiO2 is determined as optimal at 3wt%.

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Most of the research work focussed on fabricating an implant material with an ideal combination of potential bioactivity on the surface and striking mechanical property of bulk in one elementary operation. Interwoven with above concept, SiO2 incorporated nanostructured titania coatings were fabricated on Ti alloy by anodization using sodium silico fluoride electrolyte (SSF). The coatings were characterized by SEM, EDS, AFM, XRD and AT-FTIR techniques.

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