Publications by authors named "M Muallem"
Article Synopsis
- Ovarian cancer has the worst prognosis among gynecological cancers, making accurate pre-operative and intraoperative diagnosis crucial for improving patient outcomes.* -
- A study reviewed 156 cases of ovarian masses, comparing final histological diagnoses with ultrasound, MRI, and frozen section (FS) to determine diagnostic accuracy; FS showed high sensitivity for detecting malignancies.* -
- While FS is effective for diagnosing ovarian tumors, the study highlights ongoing challenges in accurately diagnosing borderline ovarian tumors using both imaging techniques and FS.*
Purpose: With growing knowledge about ovarian cancer over the last decades, diagnosis, evaluation and treatment of ovarian cancer patients have become highly specialized, and an individually adapted approach should be made in each woman by interdisciplinary cooperation. The present study aims to show the variety and extent of medical specialties involved at our institution according to the European Society of Gynecologic Oncology (ESGO) Quality indicators (QI).
Methods: A woman, diagnosed with high-grade ovarian cancer, International Federation of Gynecology and Obstetrics (FIGO) class IVb was selected for a single case observational study.
Cervical cancer is still the fourth most common cancer in women throughout the world; an estimated 604,000 new cases were observed in 2020. Better knowledge of its pathogenesis, gained in recent years, has introduced new preventive and diagnostic approaches. Knowledge of its pathogenesis has made it possible to provide individualized surgical and drug treatment.
View Article and Find Full Text PDFObjective: Nintedanib is an oral tyrosine kinase inhibitor targeting, among others, vascular endothelial growth factor receptor. The aim was to establish the role of nintedanib in addition to paclitaxel and carboplatin in first-line recurrent/metastatic cervical cancer.
Methods: Double-blind phase II randomized study in patients with first-line recurrent or primary advanced (FIGO stage IVB) cervical cancer.
Objective: Adult granulosa cell tumors represent less than 5% of all ovarian malignancies. The aim of this study was to analyze the clinicopathological parameters and their impact on progression-free and overall survival.
Methods: Patients with primary adult granulosa cell tumors treated in three international referral centers between July 1999 and December 2018 were included.