Inflammation biomarkers in the intracranial blood are associated with outcome in patients with ischemic stroke.

Background: Performing endovascular treatment (EVT) in patients with acute ischemic stroke (AIS) allows a port of entry for intracranial biological sampling.

Objective: To test the hypothesis that specific immune players are molecular contributors to disease, outcome biomarkers, and potential targets for modifying AIS .

Methods: We examined 75 subjects presenting with large vessel occlusion of the anterior circulation and undergoing EVT.

Mechanical Thrombectomy in Nighttime Hours: Is There a Difference in 90-Day Clinical Outcome for Patients with Ischemic Stroke?

Background And Purpose: Few data are available regarding the influence of the timing of ischemic stroke management, such as daytime and nighttime hours, on the delay of mechanical thrombectomy, the effectiveness of revascularization, and clinical outcomes. We aimed to investigate whether admission during nighttime hours could impact the clinical outcome (mRS at 90 days) of patients with acute ischemic stroke treated by mechanical thrombectomy.

Materials And Methods: We retrospectively analyzed 169 patients (112 treated during daytime hours and 57 treated during nighttime hours) with acute ischemic stroke in the anterior cerebral circulation.

Favorable revascularization therapy in patients with ASPECTS ≤ 5 on DWI in anterior circulation stroke.

Background: A low baseline Alberta Stroke Programme Early CT Score (ASPECTS) is strongly associated with low rates of favorable outcome in patients with acute stroke.

Objective: To evaluate the efficacy and safety of revascularization therapy in patient with ASPECTS ≤5 in anterior circulation infarct.

Methods: We retrospectively analyzed 108 consecutive patients presenting low ASPECTS on diffusion-weighted imaging.

Submandibular puncture of the facial vein: an original route for endovascular therapy of cavernous sinus dural fistulas.

Introduction: Carotid cavernous sinus fistulas are a potentially severe pathology. Their basic standard treatment is an occlusion of the CCF performed by retrograde venous catheterization via the inferior petrous sinus. When the inferior petrous sinuses are occluded, other alternative venous routes are possible with various subsequent difficulties and risks.

Mechanical thrombectomy in acute ischemic stroke: catch device.

Background And Purpose: Mechanical thrombectomy presents today a promising alternative to traditional stroke therapies. Our aim with this study was to evaluate the safety and efficacy of the Catch mechanical thrombectomy device in the treatment of acute stroke and report the angiographic results and clinical outcomes.

Materials And Methods: We performed an analysis of 40 consecutive patients with ischemic stroke treated with the Catch device at our academic center.