Changes in fluorescein angiogram early after surgical removal of choroidal neovascularization in age-related macular degeneration.

Background: Retinal pigment epithelial (RPE) defects inevitably occur in surgical removal of choroidal neovascularization (CNV) in age-related macular degeneration (AMD). RPE can proliferate and cover the denuded area, but the healing process has not been investigated in humans. To understand the RPE wound-healing process, we estimated the changes in fluorescein angiograms early after CNV removal.

[Visual outcome of macular hole surgery with internal limiting membrane peeling].

Purpose: To evaluate the efficacy of the internal limiting membrane(ILM) peeling on macular hole surgery.

Methods: A series of 102 patients(105 eyes) who underwent primary macular hole surgery between October 1994 and April 1999 was used for this retrospective study. The mean age was 65.

Optical cross-sectional evaluation of successfully repaired idiopathic macular holes by retinal thickness analyzer.

Purpose: To describe optical cross-sectional images of successfully repaired idiopathic macular holes and to determine the influences of epiretinal membranes and retinal pigment epithelial (RPE) changes on foveal reconstruction and the correlation between retinal thickness and postoperative visual acuity.

Methods: In a prospective study, optical cross-sectional imaging and retinal thickness measurement of the macula using a retinal thickness analyzer were performed on 63 eyes of 63 patients who underwent successful macular hole surgery.

Results: Cross-sectional images of foveal reconstruction were morphologically categorized into four patterns: normal fovea (23 eyes [37%]), cavernous fovea (19 eyes [30%]), flat fovea (11 eyes [17%]), and irregular fovea (10 eyes [16%]).

Two-year follow-up study comparing primary vitrectomy with scleral buckling for macula-off rhegmatogenous retinal detachment.

Purpose: To compare the anatomic and visual outcomes achieved by scleral buckling and primary vitrectomy for the repair of macula-off rhegmatogenous retinal detachment.

Methods: The records were reviewed for a consecutive series of 167 patients (167 eyes) who were initially treated with scleral buckling or pars plana vitrectomy for primary macula-off retinal detachment. Patients were treated between January 1993 and December 1996.

White thread-like retinal arterioles associated with antiphospholipid antibody syndrome.

Background: Report of 2 patients with antiphospholipid antibody syndrome (APS) who had elevated anti-beta2-glycoprotein I antibodies and showed white thread-like retinal arterioles.

Cases: A complete ophthalmological examination was conducted on 2 patients who presented with blurred or distorted vision. Fluorescein angiography was used to examine the integrity of the retinal circulatory system.