Publications by authors named "M Most"

Brucella canis is a zoonotic pathogen and the main causative agent of canine brucellosis. In the Netherlands, B. canis had previously only been detected in individual cases of imported dogs.

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Article Synopsis
  • The environmental effects of pharmaceuticals like fluoxetine, an antidepressant, have raised concerns, particularly regarding non-monotonic dose-response curves (NMDRs), which complicate risk assessments at low exposure levels.
  • A framework by the European Food Safety Authority provides six checkpoints for evaluating NMDR datasets, helping to systematize their assessment.
  • In analyzing 53 datasets, the study found that while some supported NMDR relationships for fluoxetine, many studies lacked strong evidence or did not meet critical assessment criteria, highlighting the need for better understanding of NMDRs in ecotoxicology.
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Intrauterine growth-restricted (IUGR) fetuses exhibit systemic inflammation that contributes to programmed deficits in myoblast function and muscle growth. Thus, we sought to determine if targeting fetal inflammation improves muscle growth outcomes. Heat stress-induced IUGR fetal lambs were infused with eicosapentaenoic acid (IUGR+EPA; = 9) or saline (IUGR; = 8) for 5 days during late gestation and compared to saline-infused controls ( = 11).

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Campylobacter is the most reported zoonotic pathogen in humans in the European Union. Poultry is a major source of human infection with Campylobacter. Although many studies are done on the presence of Campylobacter in broilers and theoretically effective control measures are known, their relative importance at broiler farms remains poorly understood.

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The nematode is a valuable model for ecotoxicological research, yet limited attention has been given to understanding how it absorbs, distributes, metabolizes, and excretes chemicals. This is crucial for because the organism is known to have strong uptake barriers that are known to be susceptible to potential confounding effects of the presence of as a food source. One frequently studied compound in is the antidepressant fluoxetine, which has an active metabolite norfluoxetine.

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