Publications by authors named "M Mosadegh"

Article Synopsis
  • Apoptosis, or programmed cell death, is vital for tissue balance, and its disruption is linked to diseases like cancer and neurodegenerative disorders.
  • The review explores the molecular mechanisms and signaling pathways of apoptosis, including how the tumor microenvironment affects treatment resistance in cancer.
  • It also discusses new therapeutic strategies, including natural compounds and dietary supplements, that aim to modify apoptotic processes to improve disease management and cancer treatment outcomes.
View Article and Find Full Text PDF

Background: The current study aimed to evaluate the prognostic value of serum amyloid A protein)SAA(protein as a biomarker in diagnosing 2019 novel coronavirus disease)COVID-19(infection.

Methods: The study was conducted on 123 patients with definitive COVID-19 infection referred to Shahid Beheshti and Sina hospitals in Hamedan province, Iran. Five-milliliter blood samples were taken from all included patients and serum was isolated using a centrifuge at 10,000 rpm for 10 min.

View Article and Find Full Text PDF

Background: Parvoviruses, characterized by their tropism for blood cells, can manifest as asymptomatic infections. With their ability to persist in blood, assessing the prevalence of Parvovirus B19 (B19V) and Parvovirus 4 (PARV4) among healthy blood donors is essential for evaluating the potential transmission risks through blood transfusions, emphasizing the need for comprehensive screening protocols.

Methods: Four hundred blood donors participated in the study, with their blood specimens subjected to Real-Time PCR analysis for B19V and PARV4 nucleic acids after obtaining informed consent.

View Article and Find Full Text PDF

Background And Aims: The current study aimed to evaluate the efficiency of Enzyme-linked immunosorbent assay (ELISA) assay and monoplex and multiplex real-time reverse-transcription PCR (rRT-PCR) in the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A and B viruses (Flu A and Flu B).

Methods: The SARS-CoV-2 -specific IgG and IgM antibodies, as well as, Flu A (H1N1 and H3N2 serotypes) and Flu B virus antibodies were determined by ELISA assay. The one-step qRT-PCR method was used to detect the SARS-CoV-2 in nasopharyngeal swab samples.

View Article and Find Full Text PDF

Background: () population plays a significant role in the spread of numerous diseases in urban environments. The present study is aimed at investigating the presence of (), , (), toxigenic, and in captured from urban areas of Tehran, Iran.

Methods: From October 2021 to October 2022, 100 urban rats were trapped in 5 different districts of Tehran, Iran.

View Article and Find Full Text PDF