Publications by authors named "M Morooka"
Background: The efficacy of deep brain stimulation (DBS) in treating tremor symptoms in cerebellar disorders remains unclear.
Case Presentation: A 47-year-old woman presented with neck and arm tremor and ataxic speech/gait after four days of >40 °C fever due to septic shock attributed to lithiasis-pyelonephritis. Left ventral intermediate nucleus thalamus DBS alleviated contralateral postural arm tremor, although the action tremor and terminal oscillation remained unchanged.
Age-specific differences of Impella support in Japanese patients: The Japanese Registry for Percutaneous Ventricular Assist Device (J-PVAD) registry analysis on outcomes and adverse events.
J Cardiol
November 2024
Background: The association between the clinical significance and prognostic impact of catheter-based micro-axial ventricular assist device Impella (Abiomed, Danvers, MA, USA) support and age has not been sufficiently investigated.
Methods And Results: A total of 5282 patients treated with Impella were analyzed from the Japanese registry for Percutaneous Ventricular Assist Device (J-PVAD). Patients were categorized into four age groups: <50 years old (Group A, n = 670), 50-69 years old (Group B, n = 2009), 70-79 years old (Group C, n = 1716), and ≥80 years old (Group D, n = 887).
Article Synopsis
- A nationwide survey in Japan assessed multifocal motor neuropathy (MMN), determining its prevalence at 0.40 per 100,000 individuals and identifying 507 estimated patients.
- Most patients were male (2.3:1 ratio), with a median age of onset at 42 and an average diagnosis delay of 25 months.
- Immunoglobulin therapy was administered to 98% of patients, with 91% showing improvement, though slight neurological progression was noted over time.
Late kidney injury (LKI) in patients with acute heart failure (AHF) requiring intensive care is poorly understood.We analyzed 821 patients with AHF who required intensive care. We defined LKI based on the ratio of the creatinine level 1 year after admission for AHF to the baseline creatinine level.
View Article and Find Full Text PDFEffects of motor cortical and peripheral axonal hyperexcitability on survival in amyotrophic lateral sclerosis.
J Neurol Neurosurg Psychiatry
July 2024
Background: Increased 'cortical' and 'peripheral' excitability are reportedly associated with shorter survival in amyotrophic lateral sclerosis (ALS) patients, suggesting that hyperexcitability contributes to motor neuron death. However, whether upper or lower motor function has a greater impact on survival is unclear. We aimed to investigate the component that strongly impacts the prognosis of ALS.
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