Publications by authors named "M Moroi"

Acute adverse reactions to COVID-19 mRNA vaccines are a major concern, as autopsy reports indicate that deaths most commonly occur on the same day of or one day following vaccination. These acute reactions may be due to cytokine storms triggered by lipid nanoparticles (LNPs) and anaphylaxis induced by polyethene glycol (PEG), both of which are vital constituents of the mRNA-LNP vaccines. Kounis syndrome, in which anaphylaxis triggers acute coronary syndrome (ACS), may also be responsible for these cardiovascular events.

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  • Surgeons often leave a residual atrial-level communication during Tetralogy of Fallot (TOF) repairs, and this study aimed to see how closing this communication affects patient recovery.
  • The researchers reviewed records of 132 TOF patients who had surgery before 12 months old, comparing outcomes between those with and without the communication.
  • The results showed no significant differences in key recovery metrics like cardiac output, drug therapy duration, or intensive care stay, suggesting that closing the communication doesn't significantly alter short-term or mid-term recovery outcomes.
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Background: We investigated whether drug-coated balloon (DCB) treatment is effective for all de novo cases of coronary artery disease (CAD) in patients with diabetes mellitus. Furthermore, we also investigated the relationship between the degree of diabetes mellitus and clinical outcomes after DCB treatment.

Methods: In this study, we included 516 consecutive patients with de novo CAD who were treated with DCB.

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  • Donation after circulatory death heart transplantation may expand donor options, particularly benefiting patients with lower urgency status who are using durable left ventricular assist devices (LVADs).
  • A study analyzed data from the United Network for Organ Sharing between 2019 and 2022, comparing outcomes of heart transplant recipients with LVADs to those receiving other bridging support, focusing on one-year mortality and several medical complications.
  • While the one-year mortality rates showed no significant difference, patients with LVADs experienced higher rates of acute rejection, suggesting the need for careful monitoring and management post-transplant.
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  • This study analyzed the outcomes of 774 adult patients who received simultaneous heart-kidney transplants (SHK) under the revised UNOS heart allocation policy, focusing on 50 patients who were supported by veno-arterial extracorporeal life support (VA-ECLS) compared to 724 without.
  • Results showed that VA-ECLS patients were younger and had better kidney function before transplant but faced higher rates of temporary dialysis and lower survival rates after the procedure, with significant differences in early mortality and cardiac allograft failure.
  • The findings indicate that while VA-ECLS patients have similar renal outcomes post-transplant, they experience greater risks for early mortality and complications related to heart trans
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