Retigabine increases the conformational stability of the visual photoreceptor rhodopsin.

Rhodopsin is the key photoreceptor protein that mediates vision in low-light conditions. Mutations in rhodopsin are the cause of retinal degenerative diseases such as retinitis pigmentosa. Some of these mutations cause a decreased stability of the receptor.

Quantum reinforcement learning in the presence of thermal dissipation.

A study of the effect of thermal dissipation on quantum reinforcement learning is performed. For this purpose, a nondissipative quantum reinforcement learning protocol is adapted to the presence of thermal dissipation. Analytical calculations as well as numerical simulations are carried out, obtaining evidence that dissipation does not significantly degrade the performance of the quantum reinforcement learning protocol for sufficiently low temperatures, in some cases even being beneficial.

Effect of Trace Metal Ions on the Conformational Stability of the Visual Photoreceptor Rhodopsin.

Trace metals are essential elements that play key roles in a number of biochemical processes governing human visual physiology in health and disease. Several trace metals, such as zinc, have been shown to play important roles in the visual phototransduction process. In spite of this, there has been little research conducted on the direct effect of trace metal elements on the visual photoreceptor rhodopsin.

System size synchronization.

In this paper we bring out the existence of a kind of synchronization associated with the size of a complex system. A dichotomic random jump process associated with the dynamics of an externally driven stochastic system with N coupled units is constructed. We define an output frequency and phase diffusion coefficient.