This paper focuses on the modeling, control, and simulation of an over-actuated hexacopter tilt-rotor (HTR). This configuration implies that two of the six actuators are independently tilted using servomotors, which provide high maneuverability and reliability. This approach is predicted to maintain zero pitch throughout the trajectory and is expected to improve the aircraft's steering accuracy.
View Article and Find Full Text PDFMultidrug-resistant bacteria cause over 700,000 deaths annually, a figure projected to reach 10 million by 2050. Among these bacteria, the ESKAPEE group is notable for its multiple resistance mechanisms. Given the high costs of developing new antimicrobials and the rapid emergence of resistance, drug repositioning offers a promising alternative.
View Article and Find Full Text PDFInt J Environ Res Public Health
December 2024
This study examined the associations between age, adiposity, physical activity, sedentary behavior, and elevated blood pressure (BP) in 2901 Portuguese children and adolescents aged 2-18. BP, body mass index (BMI), waist-to-height ratio (WHtR), physical activity, and sedentary behavior were measured. Elevated BP was defined as a BP above the 90th percentile for age, sex, and height.
View Article and Find Full Text PDFBiomimetics (Basel)
December 2024
In this contribution, a methodology for the optimal tuning of controllers of complex systems based on meta-heuristic techniques is proposed. Two bio-inspired meta-heuristic optimization algorithms -the Antlion Optimizer (ALO) and the Whale Optimization Algorithm (WOA)- have been applied to two different dynamic systems: the Hoop & Ball electromechanical system, a system where a linearized description is adequate; and to a Wind Turbine-Generator-Rectifier, as an example of a complex non-linear dynamic system. The performance of the ALO and WOA techniques for the tuning of conventional PID controllers is evaluated in relation to the number of agents nS and the maximum number of iterations nMaxIter; given the stochastic nature of both methods, repeatability is also addressed.
View Article and Find Full Text PDFIn this article, we aim to evaluate the effects of photobiomodulation on mitochondria quantity, biogenesis, and mitophagy-associated genes in breast cancer (BC) cells. Both models were irradiated with a low-power infrared laser (880 nm, 150 mW) and amber LED (617 nm, 1500 mW), alone or simultaneously. We evaluated the mRNA expression of PINK1 and PGC-1α genes, and the mitochondrial number was assessed based on the ratio of mitochondrial DNA/genomic DNA (mtDNA/gDNA).
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